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Brain Bank
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AIIMS Bhubaneswar
Indian Council of Medical Research
Brain Bank Network India Initiative

Brain Bank Network India Initiative

AIIMS Bhubaneswar Brain Bank

“In Service of Science, Preserving the Human Brain”

Welcome to the “Brain Bank Network India Initiative”: Establishment of satellite Brain banks in India for Neuroscience Research Funded by ICMR.

Our Brain Bank is committed to unlocking the fundamental principles of brain function and dysfunction by enabling access to high-quality human tissue catalyzing discoveries that shape the future of medicine and society.

Our Mission: “Advancing Neuroscience Through the Preservation of Human Brain Tissue” We aim to bridge donors and discovery, creating a vital repository that supports global research efforts to decode neurological disorders and improve human health.

AIIMS Bhubaneswar campus

Donation

Contribute Through Brain Donation

Play a vital role in advancing research by learning how brain tissue donation supports scientific breakthroughs.

Museum

Visit the Human Brain Museum

Step into the region’s first brain museum, showcasing fascinating exhibits and immersive learning experiences. (Open for educational visits)

Research

Explore & Learn

Use our interactive resources to better understand the remarkable complexity of the human brain.

About Us

ABOUT US

At the AIIMS Bhubaneswar Brain Bank, we are committed to driving progress in neuroscience by enabling access to carefully preserved, high-quality brain tissue that supports scientific breakthroughs. AIIMS HBTR was established in year 2021 in the Department of Pathology and Lab medicine. The brain remains one of the most complex and least understood organs, and through brain donation, you can help change that. By preserving donated brain tissue with the highest care and respect, we support research that seeks to understand conditions like Parkinson’s, dementia, stroke, Alzheimer’s, and other neurological disorders that affect millions of lives.

Every donation tells a story. Every sample brings scientists one step closer to answers to challenging questions and enables better diagnosis, improved treatments, and, ultimately prevention of such neurological conditions. Behind this effort is a dedicated team of doctors, researchers, and specialists working together to ensure that each contribution becomes a powerful resource for science.

“Be Part of the Journey: Help us unravel the brain’s mysteries and advance medicine for generations to come.”

Objective 1. To establish satellite Brain Banks in India for promoting research in neuroscience.

  • Develop, standardize, and harmonize protocols for collection, freezing, and neuropathological diagnosis among satellite Bio Banks/Brain Banks
  • Develop gold standards for tissue handling, safety, quality control and ethics and evaluate cost effective methods of tissue preservation applicable to our country
  • Capacity building & manpower development through workshops and short-term training programs in Bio banking practices
  • Popularize tissue/ organ donation among professionals and community to promote research

Objective 2. Networking of satellite Brain Banks with NIMHANS as nodal Centre

  • Develop common database of cases as per protocols developed for minimal clinical information to accompany the cases. Data will be centrally held in NIMHANS Brain Bank server for satellite banks to access.
  • Develop website for researchers to access database and send requests for tissues online
  • Establish guidelines and protocols for transparency in exchange of tissues and fluids with other Bio Banks to promote research in line with ICMR guidelines for Biomedical Research.
  • This network will be registered with other networks such as ISBER
  • Set up satellite Brain Museums as national resource for medical and public education.

Future Perspectives

Future Perspectives of AIIMS Bhubaneswar HBTR & Neuropathology Museum

Neurodegenerative Diseases

  • Explore and understand the mechanistic links behind dementia in aging process.
  • Creation of a spatial transcriptomic atlas of human brain aging in Indian Population
  • Characterize and standardize serological diagnostic test for Central nervous system infective diseases

Molecular Biology

  • Transcriptomic analysis of the human Rabies cases.
  • Transcriptomic profiling of hemorrhagic stroke and unravel the key mechanisms post stroke.
  • Development of cDNA library in normal and neurodegenerative diseases.
  • Development of a DNA bank as a research facility for genetically transmitted neurological diseases in collaboration with other laboratories.

Infections

  • The neuropathological evaluation of tubercular meningitis and its pathogenesis in the Indian context.
  • Immuno profiling in Neuroinfections, epilepsy and their influence on progression of the disease
  • Proteomics/genomics of CNS infections to identify candidate biomarkers
  • Establishment of registries and developing database of Neuroinfections for policy planning.

Stem cell biology

  • Mapping of resting stem cell pool in the human brain at different ages.
  • Response of resting stem cells following head injury and their reparative potential.
  • Identifying tumor stem cells in human brain tumors.

Teaching modules

  • Developing museum and teaching sets to provide material to medical colleges for undergraduate and postgraduate training

MRI imaging

  • MRI imaging of human brain specimens collected at autopsy for Neuroanatomical and pathological correlation.

Free of freezing artefacts

  • Development of technology to retrieve brain tissue from frozen state for histological processing without freezing artefacts. Though the technology for such retrieval of cell lines is available, for small bits, from large slices of brain, it needs to be developed. This will facilitate the simultaneous pathomorphological and molecular biological studies in future from the stored material and correlate with MRI and molecular imaging in human brain.

Networking

  • Make efforts to enroll and develop Biobanks in the country by networking with likeminded medical colleagues and popularize autopsy service as a vital teaching activity for the medical students.

Our Collaborations

Our Collaborations

We are proud to collaborate with two leading institutions in neuroscience research:

NIMHANS

National Institute of Mental Health and Neurosciences

A globally recognized leader in brain research, contributing cutting-edge expertise and resources to support our mission.

NIMHANS Brain bank site

PGIMER

Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh

Partnering with us to advance neurological research, PGIMER Chandigarh provides critical clinical insights and research collaboration.

PGIMER Brain bank Site

These collaborations help enhance the quality of our research, ensuring that our work is impactful and far-reaching in the field of neuroscience.

Faculty and Staff

Faculty and Staff

Dr. Suvendu Purkait

Dr. Suvendu Purkait

Additional Professor, Project Investigator

Dr. Sanjeev Kumar Bhoi

Dr. Sanjeev Kumar Bhoi

Professor and Head, Co-PI

Dr. Manoj Kumar Mohanty

Dr. Manoj Kumar Mohanty

Professor and Head, Co-PI

Dr. Rabi Narayan Sahu

Dr. Rabi Narayan Sahu

Professor and Head, Co-PI

Potnuru Gouri Sankar Das

Potnuru Gouri Sankar Das

Project Research Scientist

Soumyasree Dutta

Soumyasree Dutta

Technical Support

Prajnya Paramita Maharana

Prajnya Paramita Maharana

Data Entry Operator

Samita Ghadei

Samita Ghadei

Lab Attendant

Sanjay Kumar Nayak

Sanjay Kumar Nayak

Lab Attendant

Research and Education

Research and education

We can add overview option in which we can add dissection images and procedure. (LIKE in NIMHANS)

Effect of Post-mortem interval (PMI) on the histopathological and Immunohistochemical assessment Brain tissue with different PMI (1 to >30 hrs.) was assessed for an objective decay score on histopathology and different immunohistochemistry related to the basic structure and enzymes related to ROS metabolism. In the process of manuscript preparation

Effect of Post-mortem interval (PMI) on the DNA and RNA integrity of the tissue Brain tissue with different PMI was assessed for RNA integrity and DNA integrity by different methods.

Different region of the mRNA of Cytochrome C1 (CYC1) was assessed with qRT-PCR In the process of manuscript preparation

Assessment of the pathobiology of Cerebral Small Vessel disease (CSVD). The expression of different molecular markers related to ferroptosis form of cell death was assessed in CSVD cases.

Multimodal Evaluation of RNA Integrity and Tissue Quality in Human Postmortem Brain Across Varying Postmortem Intervals in a Tropical Indian Brain Biobank

To train the residents perusing MD pathology on brain autopsy, anatomical dissection, histopathological assessment and storage of brain tissue.

Development of the skill and competence of the MD Pathology residents for performing brain autopsy and dissection independently.

Preliminary diagnosis of the gross and microscopic pathology.

BRAIN Museum

Mission

Sow the seeds of Neuroscience, Make everyone N-Literate (Neuroscience Literate)

The Human Brain Museum at AIIMS Bhubaneswar offers a unique opportunity to explore the complexities of the human brain. Visitors can learn about brain anatomy, neurological disorders, and the importance of brain tissue donation for scientific research.

Visit Us: Find details on visiting hours, booking group tours, and museum guidelines.

GeNERal information

Thank you for showing your interest in visiting Department of Pathology and Lab medicine, 2nd floor, Academic Block, All India Institute of Medical Sciences, Bhubaneswar,

With regards to visit to Human Brain Museum, here is the procedure and instructions to be followed to book an appointment for your proposed pathology Brain Museum visit.

  • Book an online appointment or write an email at (EMAIL ID), requesting to permit your school for the proposed museum visit.
  • Wait for the confirmation email from Brain Museum Staff for the with visit/appointment details and instructions.
  • Instruction and procedure prior to visit to the museum.
Points to Note
  • Please note students of grade-8 and above are the given permission for museum visit. The lower grades i.e., from class 1-7 are not given appointments for Museum Visit.
  • Please note if the number of students per batch are more than 35, multiple visits shall be proposed. This will ensure proper management and smooth conductance of the guided tour. We don’t accept the visit when the total number of students and teacher together crosses 40 as we have space constrain. If the school has more students, they should divide them into batches not crossing 40. If more than 40 students reach the museum the trip may be cancel, refusing the entry for logistics reasons.
  • In case if two school simultaneously book the same slots the priority will be given on the basis of: "First cum First service"
  • Please provide the contact details of the accompanying faculty/teacher.
  • School & Colleges (group bookings) are not permitted on all Saturdays (whole day) and on all Wednesday afternoons as these days, museum is exclusively reserved for the general public entry.
  • We may not be able to fix the visit to the Brain Museum according to your convenience. The date will be fixed by Co-coordinator, Brain Museum & the school/college are expected to follow it carefully.
  • This proposed schedule is valid only to visit Brain Museum. please contact respective Officer In Charge.
  • Museum remains close on all 2nd Saturdays, Sundays & Public holidays.
Appointment Booking Form (Check NIMHANS site for this)

Write an email at (email id), requesting to permit your school for the proposed museum visit – Kindly check the calendar for the earliest available slot for booking Neuropathology Museum Visit to your Institute

  • Name of the Institute/Organization
  • Course/Board of study (if applicable)
  • Year/Class of study (if applicable)
  • Number of students/visitors
  • Has your school have earlier visited the museum. If yes, please specify the number of visit/per year and also the years of visit.
  • Accompanying teachers name and contact details to be mentioned in the email while booking for appointment.
  • Names of the students on the letter head of the school/college, duly signed by the respective head of the institute as a word attachment should be sent.
  • Foreign students sent by the respective institute should send the names of the students, Date of arrival to India, Date of Departure, and Contact Details of the students on the letter head of the school/college, duly signed by the respective head of the institute as a word attachment should be sent.

Personal information

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Contact Us

Department of Pathology and Lab medicine

Department of Pathology and Lab medicine,

Academic Block, AIIMS Bhubaneswar.

+91 96540 45753

Contact US for more information